Abstract #1225

New 4D-MRA approach named 4D-APACK by integrating 4D-PACK and AccASL for visualization of long transit time artery: Investigating hemodynamics accuracy and AVM clinical case

Yuta Akamine¹, Makoto Obara¹, Osamu Togao², Shuhei Shibukawa³, Masami Yoneyama¹, Tomoyuki Okuaki¹, and Marc Van Cauteren⁴

¹Philips Japan, Shinagawa, Tokyo, Japan, ²Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan, ³Department of Radiology, Tokai University Hospital, Kanagawa, Japan, ⁴Philips Healthcare, Shinagawa, Tokyo, Japan

A new 4D-MRA approach named 4D-AccASL-PACK (4D-APACK) was implemented and images were acquired in six healthy volunteers and one AVM patient. 4D-APACK consists of 4D-PACK and acceleration-selective arterial spin labeling (AccASL) for obtaining efficiently both dynamic information and ATT independent visualization of very slow flow. 4D-APACK replaces last timepoint data of 4D-PACK with AccASL. To investigate hemodynamics accuracy for 4D-APACK, ATT correlation between 4D-pCASL and 4D-APACK and contamination of sinuses were measured. The vessel visualization of MCA M1 to M4 were compared with 4D-pCASL. We demonstrate that 4D-APACK brings reliable hemodynamic information comparable to 4D-pCASL, while retaining MCA visualization performance.

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