We present a multi-center, multi-vendor study evaluating repeatability and reproducibility of quantitative MRI data acquired using high resolution (1 mm³) multi-parameter mapping which provides quantitative R1, MT and R2* maps of the whole brain within less than 18 min. The protocol was implemented at four clinical sites with different Siemens and Philips 3T MRI scanners. Scan-rescan measurements of the same five healthy volunteers at all sites showed good intra-site reproducibility in all parameter maps. However, the inter-site comparisons showed higher reproducibility within a single vendor than across vendors.
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