1Center for Mind/Brain Sciences-University of Trento, Trento, Italy, 2Department of Psychology and Cognitive Science-University of Trento, Trento, Italy, 3IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy, 4Service of Statistics, IRCCS Fatebenefratelli, Brescia, Italy, 5IRCCS, Istituto di Ricerche Farmacologiche Mario Negri, Milano, Italy, 6Department of Physiology and Pharmacology, University of Rome, Rome, Italy, 7Sapienza University of Rome, Rome, Italy, 8Aix-Marseille Universitè, Marseille, France, 9Alzheimer’s Disease Unit and Other Cognitive Disorders Unit, Hospital Clinic de Barcelona, Barcelona, Spain, 10University of Genoa, Genoa, Italy, 11Lab of Clinical Neurochemistry, University of Perugia, Perugia, Italy, 12INSERM, Imagerie Cerebrale et Handicaps Neurologiques, Toulouse, France, 13Catholic University, Policlinico Gemelli, Rome, Italy, 14University of Leipzig, Leipzig, Germany, 15Fondazione SDN per la Ricerca e l’Alta Formazione in Diagnostica Nucleare, Naples, Italy, 16Aristotle University of Thessaloniki, Thessaloniki, Greece, 17Alzheimer Center, Amsterdam Neuroscience, VU University Medical Center, Amsterdam, Netherlands, 18VU University Medical Center, Amsterdam, Netherlands, 19University Medical Center, Goettingen, Georg-August-University, Goettingen, Germany, 20Service de Pharmacologie-Hôpital Huriez-CHRU, Lille, France, 21GSK, Neurosciences Therapeutic Area, Brentford, United Kingdom, 22Mediterranean Institute of Cognitive Neurosciences, Marseille, France, 23Memory Clinic and LANVIE - Laboratory of Neuroimaging of Aging, University Hospitals and University of Geneva, Geneva, Switzerland, 24Laboratory of Alzheimer’s Neuroimaging and Epidemiology - LANE, IRCCS Institute - The Saint John of God Clinical Research Centre, Brescia, Italy