Abstract #1134

In vivo Simultaneous Measurement of δf, T1, T2, and T2* by Magnetic Resonance Fingerprinting with Quadratic RF Phase

Charlie Yi Wang¹, Simone Coppo², Bhairav Bipin Mehta², Nicole Seiberlich^1,2, Xin Yu^1,2, and Mark Alan Griswold^1,2

¹Biomedical Engineering, Case Western Reserve University, Cleveland, OH, United States, ²Radiology, Case Western Reserve University, Cleveland, OH, United States

We propose a novel Magnetic Resonance Fingerprinting pulse sequence with quadratic RF excitation phase (qRF-MRF) for the purpose of simultaneous measurement of T₂* in addition to previously established spin parameters δf, T₁, and T₂. The original bSSFP based MRF pulse sequence¹ was modified to incorporate excitation segments with quadratic RF phase to sensitize signal evolutions to T₂*. Measurements using qRF-MRF were performed in both phantom and in vivo. Maps from qRF-MRF were validated against bSSFP based MRF and Multi-GRE.

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