Quan Jiang1,2,3, Hiani Hu4, Guangliang Ding1, Esmaeil Davoodi-Bojd1, Yimin Shen4, Li Zhang1, Lian Li1, Qingjiang Li1, Michael Chopp1,2,3, and Zhenggang Zhang1,2,3
1Neurology, Henry Ford Health System, Detroit, MI, United States, 2Physics, Oakland University, Rochester, MI, United States, 3Neurology, Wayne State University, Detroit, MI, United States, 4Radiology, Wayne State University, Detroit, MI, United States
The recently discovered glymphatic
system has become an exciting area of research because of it plays an important
role in neurological diseases. However,
the interaction between the vascular and the glymphatic systems in terms of
waste clearance from the brain is not clear. In
addition to the glymphatic system, our preliminary MRI results suggest
that the venous system involves in waste removal and waste clearance increases after
diabetes. Current study provide the first investigation of the interaction
between the vascular and the glymphatic systems in brain waste clearance after
diabetes.