Evidence of Dense Functional Connectivity in the Human Brain
Ankita Saha1, Ishaan Batta2, and Rahul Garg1
1Department of Computer Science and Engineering, Indian Institute of Technology Delhi, New Delhi, India, 2Center for Biomedical Image Computing and Analytics, University of Pennsylvania, Philadelphia, PA, United States
Aimed at studying the nature of voxel-wise interactions in the brain, this study finds the evidence of dense functional connectivity in the brain using resting state fMRI data from over 700 subjects. To study the nature of these interactions, we used a bipartite graph embedding algorithm on the connectivity network obtained with multiple pre-processing strategies with respect to global signal regression. We also analyzed interactions between and whithin grey and white matter. The results point to a dense non-bipartite network covering 74.63% of the brain leading to new insights towards understanding the human functional connectome.
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