Abstract #0862

Characteristics of Plaques and Lenticulostriate Arteries in Stroke Patients by Whole-Brain Vessel Wall Magnetic Resonance Imaging

Fang Wu¹, Zhaoyang Fan², Tianyi Qian³, Qi Yang¹, and Debiao Li²

¹Department of Radiology, Xuanwu Hospital, Capital Medical University, Beijing, China, ²Biomedical Imaging Research Institute, Cedars Sinai Medical Center, Los Angeles, CA, United States, ³MR Collaboration NEA, Siemens Healthcare, Beijing, China

The aim of our study was to investigate the plaque characteristics and the lenticulostriate artery (LSA) status in artery-to-artery (A-to-A) embolism and branch atheromatous disease (BAD) using whole-brain high-resolution MRI. The results showed that patients with A-to-A embolism presented more frequently hyperintense plaques (HIP), plaque surface irregularity, and severe stenosis than patients with BAD. A signiﬁcant reduction in the number and lengths of LSA branches in patients with BAD compared to A-to-A embolism was also found. Multivariate analysis further demonstrated that HIP was independently associated with A-to-A embolism, whereas the reduction in LSA branches was independently associated with BAD.

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