Abstract #0759

Clinical value of dark-blood late gadolinium enhancement without additional magnetization preparation

Robert J. Holtackers^1,2, Caroline M. van de Heyning^2,3,4, Muhummad S. Nazir^2,3, Imran Rashid^2,3, Ioannis Ntalas^2,3, Haseeb Rahman^3,5, René M. Botnar^2,6, and Amedeo Chiribiri²

¹Department of Radiology, Maastricht University Medical Centre, Maastricht, Netherlands, ²School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom, ³Department of Cardiology, St Thomas' Hospital, London, United Kingdom, ⁴Department of Cardiology, Antwerp University Hospital, Antwerp, Belgium, ⁵British Heart Foundation Centre of Excellence, King's College London, London, United Kingdom, ⁶Pontificia Universidad Católica de Chile, Escuela de Ingeniería, Santiago, Chile

Late gadolinium enhancement (LGE) MRI often suffers from poor scar-to-blood contrast when used for detection of (sub)endocardial scar due to the bright signal of adjacent blood. We sought to validate a novel dark-blood LGE technique in a large cohort of 250 patients at both 1.5T and 3T. Combining left ventricular blood nulling with phase-sensitive inversion-recovery significantly improved both image quality and diagnostic confidence compared to conventional bright-blood LGE. As no additional magnetization preparation is used, clinical application on current MRI systems is readily available without the need for extensive simulations, software modifications and/or additional training.

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