Abstract #0627

Dynamic 23Na-Imaging of the Human Lung with Fully Flexible Intrinsic Respiratory Gating

Nicolas G.R. Behl¹, Armin M. Nagel^1,2, Reiner Umathum¹, Florian Maier¹, Mark E. Ladd¹, Mark O. Wielpütz³, Hans-Ulrich Kauczor³, and Tanja Platt¹

¹Division of Medical Physics in Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany, ²Institute of Radiology, University Hospital Erlangen, Erlangen, Germany, ³Diagnostic and Interventional Radiology, University Hospital of Heidelberg, Heidelberg, Germany

²³Na lung MRI is a potential tool e.g. for investigating tumor viability and treatment response. The acquired data is, however, influenced by respiratory motion since breath-hold acquisitions are not possible due to the long measurement times. Here, we present a method for full flexibility in retrospective gating of 3D-radial data, combined with a Compressed-Sensing reconstruction. Up to 14 frames could be reconstructed from one in-vivo dataset, corresponding to a temporal resolution of 0.27 s. The temporal resolution of ²³Na lung MRI could potentially lead to a more accurate quantification of the Tissue Sodium Concentration in the human torso.

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