Abstract #0523

Emerging Metabolic Trajectories in the Developing Fetal Brain

Subechhya Pradhan^1,2,3, Kushal Kapse¹, Reka Kovacs¹, Linda White¹, and Catherine Limperopoulos^1,2,3

¹Developing Brain Research Laboratory, Children's National Health System, Washington, DC, United States, ²Diagnostic Imaging and Radiology, Children's National Health System, Washington, DC, United States, ³Pediatrics, The George Washington University School of Medicine, Washington, DC, United States

Knowledge of metabolite changes in the fetal brain will provide insight into the biochemical changes in the developing brain. Findings from measurement of metabolite concentration as a function of increasing GA are reported. Significant increases in NAA, Cr, Cho and scyllo-Inositol with increasing GA in the fetal brain was observed in this study. Changes in myo-Inositol with GA did not reach significance.

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