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Abstract #0511

Association Between Concussion-induced Dizziness and Damage of Thalamo-cortical Connectivity after mild Traumatic Brain Injury

Chia-Feng Lu1,2,3, Yu-Chieh Jill Kao1,4, Li-Chun Hsieh1,4,5, Sho-Jen Cheng1,5, Ho-Fang Huang1,6, Wen-Jin Hsieh1,5, Fei-Ting Hsu1,4, Ping-Huei Tsai1,4, and Cheng-Yu Chen1,4,5

1Research Center of Translational Imaging, College of Medicine, Taipei Medical University, Taipei, Taiwan, 2Department of Anatomy and Cell Biology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan, 3Department of Biomedical Imaging and Radiological Sciences, National Yang-Ming University, Taipei, Taiwan, 4Department of Radiology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan, 5Department of Medical Imaging, Taipei Medical University Hospital, Taipei, Taiwan, 6Department of Medical Research, Taipei Medical University Hospital, Taipei, Taiwan

Dizziness is a frequent symptom of concussion, however neuroimaging evidence that supports clinical symptoms after mTBI was less explored. This study demonstrated the post-concussion damages of thalamo-cortical networks revealed by the axonal injuries of specific fiber tracts and the altered functional connectivity. The estimates of Dizziness Handicap Inventory significantly correlated to the functional connectivity of thalamic nuclei.

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