Abstract #0485

In Vivo Quantification of Aortic Stiffness in Abdominal Aortic Aneurysm Patients using MR Elastography: A Longitudinal Study

Huiming Dong^1,2, Brian Raterman¹, Xiaokui Mo³, Prateek Kalra¹, Richard White¹, and Arunark Kolipaka¹

¹Department of Radiology, The Ohio State University Wexner Medical Center, Columbus, OH, United States, ²Department of Biomedical Engineering, The Ohio State University, Columbus, OH, United States, ³Center for Biostatistics, The Ohio State University, Columbus, OH, United States

Abdominal aortic aneurysm (AAA) rupture causes death in 90% of AAA patients. Clinically, the rupture potential is evaluated using AAA diameter. Aortic stiffness can potentially provide more accurate rupture risk assessment. Therefore, the aim of this study is to use non-invasive MR elastography (MRE) to estimate aortic stiffness in AAA patients, and study the relationship between stiffness and AAA diameter. Results showed that aortic stiffness varied during the serial follow-up, demonstrating (1) no correlation between AAA stiffness and diameter, and (2) AAA diameter may not be an accurate indicator for rupture potential.

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