Abstract #0443

Structural Determination Using 129Xe NMR Line-shape in Chemical Shift Imaging

Stephen Kadlecek¹, Mehrdad Pourfathi¹, Luis Loza¹, Ian Duncan¹, Kai Ruppert¹, Hooman Hamedani¹, Sarmad Siddiqui¹, Yi Xin¹, Faraz Amzajerdian¹, Harrilla Profka¹, Ryan Baron¹, Mary Spencer¹, Tahmina Achekzai¹, Shampa Chatterjee², Maurizio Cereda³, and Rahim R. Rizi¹

¹Radiology, University of Pennsylvania, Philadelphia, PA, United States, ²Physiology, University of Pennsylvania, Philadelphia, PA, United States, ³Anesthesiology and Critical Care, University of Pennsylvania, Philadelphia, PA, United States

We present a method to discriminate dissolved 129Xe spectra by tissue type and location based on local variations in T2*. Mixed contributions of parenchyma and vasculature can be separated almost completely. The method is particularly useful to high field imaging in species lacking distinct dissolved phase spectral components.

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