fMRI has limited spatial accuracy due to the vascular nature of the signal source. At high fields, sub-millimeter functional images can be acquired with the hopes of investigating cortical columns and/or layers. The efforts to improve the spatial accuracy of the signals tends to be focused on the acquisition side, rather than the analysis side. Here, we explore the use of multi-voxel pattern analysis as a means to circumvent the apparent spatial specificity limits of ultra-high field fMRI.
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