Abstract #0258

On the magnetic field and echo time dependence of the pseudo-diffusion coefficient

Andreas Julian Riexinger¹, Andreas Wetscherek², Jan Martin¹, Tristan Anselm Kuder³, Armin Nagel¹, Michael Uder¹, Bernhard Hensel⁴, Lars Müller^3,5, and Frederik Bernd Laun¹

¹Institute of Radiology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany, ²Joint Department of Physics, The Institute of Cancer Research and The Royal Marsden NHS Foundation Trust, London, United Kingdom, ³Department Medical Physics in Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany, ⁴Center for Medical Physics and Engineering, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany, ⁵CUBRIC, School of Psychology, Cardiff University, Cardiff, United Kingdom

It has been reported that a strong echo time dependence of the perfusion fraction f exists in liver and pancreas. The purpose of this work is to investigate whether a similar dependence exists for the pseudo-diffusion coefficient D*. Thereto, the livers of six healthy volunteers were examined at two echo times (TE = 40/80 ms) at two field strengths. In contrast to f, D* shows almost no echo time dependence in the healthy liver and the observed field strength dependence was smaller than the fit uncertainty.

This abstract and the presentation materials are available to members only; a login is required.

Join Here