A new technique, termed Echo Planar Time-resolved Imaging (EPTI), was developed to address EPI’s geometric distortion and blurring, and to provide new temporal signal evolution information across the EPI readout window. Using only a few shots, a time-series of multi-contrast images can be created free of distortion and blurring (up to 100 T2- and T2*-weighted images with time interval of an EPI echo spacing). This should make EPTI useful for numerous applications where undistorted images across multiple-contrasts are desired. We demonstrated EPTI in brain to simultaneously map T2, T2*, and tissue phase, as well as to provide SWI.
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