Abstract #0202

Isotropic 3D T2 mapping of knee cartilage with a novel water excitation technique

Roberto Colotti¹, Jessica A.M. Bastiaansen¹, Patrick Omoumi¹, and Ruud B. van Heeswijk^1,2

¹Department of Radiology, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland, ²Center for Biomedical Imaging (CIBM), Lausanne, Switzerland

The goal of this study was to develop an isotropic 3D lipid-insensitive T₂ mapping technique of knee cartilage. Therefore we combined an existing isotropic 3D T₂-prepared gradient-echo T₂ mapping technique (Iso3DGRE) with the novel lipid-insensitive binomial off-resonant RF excitation (LIBRE) pulse. LIBRE pulse optimization was performed through numerical simulations and verified in phantom experiments, yielding complete fat signal nulling using a LIBRE pulse as short as 1 ms. T₂ mapping of knee cartilage performed in five healthy volunteers with LIBRE excitation allowed for improved cartilage delineation and precise T₂ values compared with normal excitation.

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