Abstract #0112

Brown Adipose Tissue Mass Measurement by Z-Spectrum Imaging

Alessandro M Scotti^1,2,3, Rongwen Tain^1,3, Weiguo Li^1,4,5, Victoria Gil⁶, Chong Wee Liew⁶, and Kejia Cai^1,3

¹Radiology, University of Illinois, Chicago, IL, United States, ²Bioengineering, University of Illinois at Chicago, Chicago, IL, United States, ³Center for MR Research, University of Illinois at Chicago, Chicago, IL, United States, ⁴Research Resource Center, University of Illinois at Chicago, Chicago, IL, United States, ⁵Radiology, Northwestern University, Chicago, IL, United States, ⁶Physiology and Biophysics, University of Illinois, Chicago, IL, United States

Brown adipose tissue (BAT) has a great relevance in metabolic diseases and has been shown to be reduced in obesity and insulin resistance patients. Currently, Dixon MRI is used to calculate fat-water fraction (FWF) and differentiate BAT from the less hydrated and more lipid-rich white fat. However, it may introduce fat-water swapping artifacts. Here, we showed that Z-Spectrum MRI can effectively measure FWF and BAT mass in vivo free from artifacts, due to the direct saturation of both water and fat protons.

This abstract and the presentation materials are available to members only; a login is required.

Join Here