Image-guided cancer therapy have the ability to integrate noninvasive imaging and minimally invasive interventions such as photothermal therapy (PTT) together to improve the precision of treatment. In the present study, we investigated magnetic resonance temperature imaging (MRTI) as a tool for non-invasive monitoring of tumor temperature distribution and changes during laser irradiation. To this end, we injected PEGylated graphene oxide (GO-PEG) to 4T1 tumor models and irradiated the tumors to induce PTT. Our studies demonstrate that MRTI, which is a feasible tool for the determination of temperature distribution, can be used to guide nanoparticle-mediated tumor photothermal therapy.
This abstract and the presentation materials are available to members only; a login is required.