The present study uses an efficient 2D, multi-shot, inversion-recovery EPI (MS-IR-EPI) acquisition that combines separately excited k-space segments after each inversion pulse together with steps in slice ordering to generate T1-maps with high SNR per unit time. We show that although the inversion times systematically vary across slices, consistent T1-maps can be generated across the whole brain. Such T1-maps provide high spatial resolution and SNR, with little image distortion and can be collected in a short acquisition time.
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