Abstract #0056

High Spatial Resolution BOLD fMRI Using Simultaneous Multislice Excitation with Echo-Shifting Gradient Echo at 7 Tesla

Shi Su¹, Na Lu², Xiaojing Long¹, Chunxiang Jiang¹, Hang Zhang¹, Ye Li¹, Rong Xue³, Haifeng Wang¹, Lijuan Zhang¹, Liang Dong¹, Xin Liu¹, and Guoxi Xie^1,2

¹Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China, ²Department of Biomedical Engineering, Guangzhou Medical University, Guangzhou, China, ³Beijing MRI Center for Brain Research, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China

Signal to noise gain at ultra-high field has pushed blood oxygen level dependent functional MRI towards high spatial resolution with the benefit of improved accuracy in functional mapping. However, the techniques available for high spatial resolution fMRI are mainly based on echo-planar imaging technique, which faces geometric distortion. In this work, we proposed a technique combining simultaneous multislice excitation with echo-shifting, which can be virtually free from distortion artifacts, for high spatial resolution fMRI. Significant activation was identified in visual and motor experiments with in-plane resolution of 1.0×1.0 mm² and an acceleration factor of 10 at 7 Tesla.

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