Abstract #0030

Portable single-sided MR: multicomponent T2 relaxometry and depth profiling with a Unilateral Linear Halbach sensor

Ashvin Bashyam^1,2, Chris J Frangieh^1,2, Matthew Li², Jason Stockmann^3,4, and Michael J Cima^2,5

¹Electrical Engineering & Computer Science, Massachusetts Institute of Technology, Cambridge, MA, United States, ²David H. Koch Institute For Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, United States, ³A. A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, United States, ⁴Harvard Medical School, Boston, MA, United States, ⁵Department of Materials Science and Engineering, Massachusetts Institute of Technology, Cambridge, MA, United States

Widely accessible, fast, and portable MR relaxometry can provide highly valuable diagnostic information in many diseases including fluid overload, dehydration, and muscle degeneration. High cost, large size, and extended acquisition time limit the use of traditional MRI for relaxometry.

We introduce a novel portable MR sensor with a large, remote, uniform magnetic field created by a Unilateral Linear Halbach array capable of performing spatially selective, multi-component relaxometry.

Strong agreement between simulation and experimental results indicates highly reliable magnet design methods. Spatial selectivity is achieved through variation of either RF pulse length or B1 frequency. Quantitative multi-component T2 relaxometry is demonstrated.

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