Highly resolved 1H decoupled spectroscopy with a shorter constant time delay using the 2D CT-PRESS with J refocusing

The 2D constant time localized sequence of CT-PRESS with J refocusing was proposed, having features of good peak resolution via ¹H decoupling along F₁ and of J refocusing by a 90-degree pulse at the first echo time. By controlling the time point of J refocusing, shorter constant time delay of T_ct can be achieved. This method was developed on a 4.7 T whole-body MR system. Phantom experiments were demonstrated using brain mixture solutions. Three resonances at 2.28 ppm of GABA C2H, 2.35 ppm of glutamate C4H and 2.44 ppm of glutamine C4H were resolved on the phantom spectra.