People with high risk of diabetes exhibited decreased ReHo in right temporal lobes, left pallidum/ lenticular nucleus/insula/Heschl gyrus and left cingulate cortex and declined fALFF in left Heschl gyrus, left supramarginal gyrus and left cingulate cortex, which is consistent with type 2 diabetes mellitus (T2DM) patients. These abnormal regions may be regarded as the endophenotype of T2DM in resting-state BOLD-fMRI.
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