Abstract #5251

Attentional modulation on the fMRI signal at human visual cortex revealed by fine timing characteristics but not amplitudes

Ying-Hua Chu¹, Jo-Fu Lotus Lin¹, Pu-Yeh Wu¹, Kevin W.-K. Tsai², Yi-Tien Li¹, Yi-Cheng Hsu¹, Shang-Yueh Tsai^3,4, Wen-Jui Kuo⁵, and Fa-Hsuan Lin^1,6

¹Institute of Biomedical Engineering, National Taiwan University, Taipei, Taiwan, ²Aim for the Top University Project Office, National Taiwan Normal University, Taipei, Taiwan, ³Institute of Applied Physics, National Chengchi University, Taipei, Taiwan, ⁴Research Center for Mind Brain and Learning, National Chengchi University, Taipei, Taiwan, ⁵Institute of Neuroscience, National Yang-Ming University, Taipei, Taiwan, ⁶Department of Neuroscience and Biomedical Engineering, Aalto University, Espoo, Finland

By asking subjects engaging a decision task of two levels of difficulty based on foveal stimuli, we measured the BOLD dynamics elicited by checkerboard flashing shown at the peripheral visual fields with two levels of attention using high precision simultaneous-multi-slice inverse imaging (SMS-InI TR = 0.1 s; 5 mm isotropic resolution). Results shown insignificant difference in the amplitude of the BOLD response by two tasks, while time characteristics of onset, time-to-half, and width differ significantly between tasks in the range of hundreds of milliseconds.

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