By using a dedicated 24-channel temporal lobe array and surface based laminar depth analysis, we revealed the tonotopic representations in the human primary auditory cortex on a 3T MRI system. We found that, compared to deep and superficial layers, the minimal inter-subject variability of the tonotopic representation and frequency tuning width were found at the middle layer. Locations in the auditory cortex with finer frequency tuning had smaller inter-subject variability. Taken together, our findings suggested that middle layer of the auditory cortex has more specific frequency preference and selectivity, consistent with neurophysiological animal studies.
This abstract and the presentation materials are available to members only; a login is required.