The utility of MR parametric mapping is limited due to the lengthy acquisition time. A Maximum Likelihood Estimation (MLE) and Parallel Imaging (PI) method is presented for MR parameteric mapping. The approach is based on a high Signal to Noise ratio (SNR) assumption such that the noise can be modelled as Gaussian and estimates the parameters that maximizes the signal from a multichannel coil. The method was tested on a multi-echo gradient-echo T2* mapping experiment in a phantom and a human brain. Accurate T2* maps were reconstructed up to an acceleration factor of 6 with a small error for phantom and human brain.
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