Critical limb ischemia (CLI) represents the most severe clinical manifestation of peripheral arterial disease (PAD). It has been proved that l lower extremity arterial stenosis and collateral circulation compensatory ability after occlusion play an important role on CLI. This study proposed a strategy for assessment of lower extremity arterial stenosis and collateral circulation compensatory ability by the noninvasive vessel-encoded arterial spin labeling (VEASL) to quantitatively assess perfusion territory of lower extremity arterial. The lower limb perfusion territory image and the angiosome map were obtained in this study, indicating the potential of VEASL for CLI assessment.
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