The zone of calcified cartilage (ZCC) is a thin layer between articular cartilage and bone. The ZCC plays an important role in the pathogenesis of osteoarthritis (OA) but has never been imaged in vivo with magnetic resonance (MR) imaging techniques. In this study we aimed to investigate the feasibility of direct imaging of the ZCC in healthy volunteers using a three dimensional (3D) ultrashort echo time (UTE) Cones sequence on a clinical whole body 3T scanner.
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