Abstract #5006

Crossing muscle fibres in the tongue resolved using constrained spherical deconvolution

Luuk Voskuilen^1,2,3, Valentina Mazzoli^2,4,5, Jos Oudeman², Ludi E. Smeele^1,6, Alfons J.M. Balm^1,6, Ferdi van der Heijden^1,7, Martijn Froeling⁸, Gustav J. Strijkers⁹, and Aart J. Nederveen²

¹Department of Head and Neck Oncology and Surgery, Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Amsterdam, Netherlands, ²Department of Radiology, Academic Medical Center, Amsterdam, Netherlands, ³Department of Oral and Maxillofacial Surgery, Academic Centre for Dentistry Amsterdam and Academic Medical Center, University of Amsterdam and VU University Amsterdam, Amsterdam, Netherlands, ⁴Biomedical NMR, Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, Netherlands, ⁵Orthopaedic Research Lab, Radboud UMCN, Nijmegen, Netherlands, ⁶Department of Oral and Maxillofacial Surgery, Academic Medical Center, Amsterdam, Netherlands, ⁷Department of Robotics and Mechatronics, MIRA Institute, University of Twente, Enschede, Netherlands, ⁸Department of Radiology, University Medical Center Utrecht, Utrecht, Netherlands, ⁹Biomedical Engineering and Physics, Academic Medical Center, Amsterdam, Netherlands

Tongue muscle architecture is suspected to be important in the prediction of speech and swallowing complications after surgery. The tongue contains areas of crossing muscle fibres unable to be resolved by diffusion tensor imaging (DTI). We show that constrained spherical deconvolution (CSD) is able to distinguish these crossing fibres ex vivo and in vivo using a clinically acceptable scan time of 10 min. Also, we show improved tractography in CSD compared to DTI, allowing segmentation of different tongue muscles which conforms to known anatomy.

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