Simultaneous multi-slice diffusion-weighted imaging (DWI) was applied on human right calf for imaging Spontaneous Mechanical Activity in Musculature (SMAM) in multiple slices in order to improve assessment of the spatial extension of these spontaneous activities. For data validation, diffusion-tensor images (DTI) were acquired with subsequent fiber tractography to fuse anatomical fiber orientation to spontaneous events in DWI. High accordance between both modalities and reliable application of simultaneous multi-slice diffusion-weighted imaging is demonstrated.
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