Abstract #4987

Measuring T1 and T2 of the small bowel wall at 3T

Hannah Grace Williams^1,2, Penny A Gowland¹, Luca Marciani², Robert Scott³, Guruprasad Aithal^2,3, and Caroline L Hoad^1,3

¹Sir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, Nottingham, United Kingdom, ²Nottingham Digestive Diseases Centre, School of Medicine, University of Nottingham, Nottingham, United Kingdom, ³NIHR Biomedical Research Unit in Gastrointestinal and Liver Diseases, Nottingham University Hospital, Nottingham, United Kingdom

Available techniques to measure in-vivo bowel permeability are inadequate for stratifying patients to identify those at risk of complications from increased bowel permeability. T₁ and T₂ measurements could potentially be indicators of changes in bowel wall structure and thus permeability. We have measured the T₁ and T₂ of the bowel wall to be 1.68±0.57 s and 0.08 ±0.02 s respectively. We found significant variations between and within subjects. However it is currently unknown whether some of these variations are real and some due to errors in the measurement process.

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