Abstract #4934

Ultrafast Dynamic Contrast Enhanced MRI of the Breast Using Compressed Sensing: A Novel Technique for Separate Visualization of Breast Arteries and Veins in Very Early Phase

Natsuko Onishi¹, Masako Kataoka¹, Shotaro Kanao¹, Hajime Sagawa², Mami Iima¹, Rena Sakaguchi¹, Akane Ohashi¹, Ayami Ohno Kishimoto¹, Marcel Dominik Nickel³, Masakazu Toi⁴, and Kaori Togashi¹

¹Department of Diagnostic Imaging and Nuclear Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan, ²Division of Clinical Radiology Service, Kyoto University Hospital, Kyoto, Japan, ³MR Application Predevelopment, Siemens Healthcare GmbH, Erlangen, Germany, ⁴Department of Breast Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan

Ultrafast dynamic contrast enhanced (UF-DCE) MRI using compressed sensing enabled very fast scanning of the breast (every 3.7 sec/frame), and separately visualized breast arteries and veins. Breasts with cancers showed significantly shorter time intervals between arterial and venous visualization than the contralateral breasts without cancers. The time intervals in the breast with cancers tended to be shorter than those in the breasts with benign lesions. Shorter time intervals in breasts with cancers may reflect higher vascularity in malignancy. UF-DCE MRI has a potential to enable the differentiation of breast cancers in very early phase (0-60sec after contrast injection).

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