Abstract #4926

Effect of Compressed Sensing Reconstruction Parameter on Ultrafast Dynamic Contrast Enhanced Breast MRI

Hajime Sagawa¹, Masako Kataoka¹, Shotaro Kanao², Natsuko Onishi², Maika Urago³, Marcel Dominik Nickel⁴, Masakazu Toi⁵, Kyoji Higashimura¹, and Kaori Togashi²

¹Department of Radiology, Kyoto University Hospital, Kyoto, Japan, ²Department of Diagnostic Imaging and Nuclear Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan, ³Kyoto University Hospital, Kyoto, Japan, ⁴Siemens Healthcare GmbH, Erlangen, Germany, ⁵Department of Breast Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan

The aim of this study is to assess the impact of the number of iterations of CS reconstruction on kinetic parameters and the image similarity in DCE-MRI of the breast. Breast examinations include ultrafast DCE-MRI using CS were conducted for 21 patients. The images were reconstructed with different numbers of iterations, and the semi-quantitative and quantitative kinetics parameters were compared. The reconstructed images were evaluated by root mean square error (RMSE) and structural similarity (SSIM) as the quantitative image evaluation. In small number of iteration, the all kinetics parameters were underestimated especially in malignant lesion with hypervascularity.

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