Damage to gonads, including the seminiferous tubules or epididymis, can diminish male fertility. Fertility research often employs mouse models, yet biopsy procedures may sometimes be incompatible with longitudinal studies. A viable non-invasive alternative may be MR. We scanned 8 mice at 9.4T, showing that internal testicular structure can be clearly observed, accurate measurements of seminiferous tubules (volume, diameter) obtained, extra-testicular tissues (e.g. epididymis) identified and spectroscopy peaks spatially localized across different tissues. This indicates that MRI/MRS could be useful in mouse models of fertility and possibly extended to human fertility studies in the future.
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