Abstract #4827

Complex Chemical Shift-Encoded MRI to Estimate Fat in Livers with Elevated Iron Content

Sarah Eskreis-Winkler^1,2, Simone Krebs¹, Alessandra Borgheresi¹, Davinia Ryan¹, Scott Reeder³, and Lorenzo Mannelli¹

¹Memorial Sloan Kettering Cancer Center, New York, NY, United States, ²New York Presbyterian Hospital/Weill Cornell Medicine, New York, NY, United States, ³University of Wisconsin

In patients with elevated liver iron, in-and-out-of-phase and IDEAL-IQ methods yield very different proton density fat fractions. In these patients, IDEAL-IQ could potentially serve as a more sensitive marker of hepatic steatosis than in-and-out-of-phase imaging, although larger studies are needed to confirm these findings. Irrespective of liver fat and liver iron content, conventional and IDEAL-IQ R2* values are highly correlated.

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