Abstract #4778

Role of DWI in guiding MRI-TRUS fusion biopsy in patients with prostate cancer: a prospective cohort study

Chandan J Das¹, Rohit Kaushal², Sanjay Sharma¹, Rajeev Kumar³, P N Dogra³, and S DattaGupta⁴

¹Radiology, All India Institute of Medical Sciences, New Delhi, India, NewDelhi, India, ²Uology, All India Institute of Medical Sciences, New Delhi, India, NewDelhi, India, ³Urology, All India Institute of Medical Sciences, New Delhi, India, NewDelhi, India, ⁴Pathology, All India Institute of Medical Sciences, New Delhi, India, NewDelhi, India

Transrectal ultrasound (TRUS) guided 12 core biopsy of prostate has a sensitivity of 39-52%. We prospectively evaluated the role of DWI in guiding MRI-TRUS fusion biopsy. MRI was performed on a 3 Tesla system. PIRAD score was assigned and PIRAD 3-5 score were subjected to targeted fusion biopsy using the Artemis device along with standard 12 core biopsies. Targeted biopsy detected a higher number (93%) of clinically significant cancers and 71% cancers were upgraded to significant cancer on targeted biopsy. Fusion biopsies guided by DWI thus provide incremental information over standard TRUS biopsies in the diagnosis of significant prostate cancer.

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