Current 3D black-blood high-resolution MRI (0.4-0.6mm isotropic) of intracranial vessel wall is limited by long scan times (~10 minutes). This study implemented a compressed sensing SPACE (CS-SPACE) sequence to reduce the scan time. The scan and reconstruction parameters were optimized in volunteers and then validated in patients. The optimized CS-SPACE protocol achieved good image quality and reliable vessel area measurements compared with SPACE, with a 37% time reduction. 0.5mm isotropic resolution can be achieved in <7 minutes, and 0.6mm3 is possible in 4 minutes. This fast intracranial vessel wall technique has potential for use in a clinical setting.
This abstract and the presentation materials are available to members only; a login is required.