Abstract #4714

Accelerated Time Resolved Phase Contrast Cerebral MRA to Evaluate Pulse Wave Velocity

Tzu Cheng Chao^1,2, Yu-Chia Cheng³, Wen-Chau Wu^4,5, Hsu-Hsia Peng⁶, Tzu-Chao Chuang⁷, Hsiao-Wen Chung^5,8, Teng-Yi Huang⁹, and Yi-Jui Liu³

¹Department of Computer Science and Information Engineering, National Cheng Kung University, Tainan, Taiwan, ²Institute of Medical Informatics, National Cheng Kung University, Tainan, Taiwan, ³Department of Automatic Control Engineering, Feng-Chia University, Taichung, Taiwan, ⁴Graduate Institute of Oncology, National Taiwan University, Taipei, Taiwan, ⁵Graduate Institute of Biomedical Electronics and Bioinformatics, National Taiwan University, Taipei, Taiwan, ⁶Department of Biomedical Engineering and Environmental Sciences, National Tsing Hua University, Hsinchu, Taiwan, ⁷Department of Electrical Engineering, National Sun Yat Sen University, Kaohsiung, Taiwan, ⁸Department of Electrical Engineering, National Taiwan University, Taipei, Taiwan, ⁹Department of Electrical Engineering, National Taiwan University of Science and Technology, Taipei, Taiwan

Time-resolved PCMRI has been applied to measure pulse wave velocity (PWV) for the assessment of aortic stiffness. However, longer scan time hinders its practice to achieve a high spatial and temporal resolution scan, especially required for the arteries inside of the head and neck. In the present work, an accelerated Time-resolved PCMRA was implemented to shorten scan time. The reconstruction combines temporal strategy and self-reference information to retain reasonable imaging quality. The results suggest that the proposed method differentiate PWV delay time from Common-Carotid artery to Middle-Cerebral arteries via Internal-Carotid artery with good quality within a 10-minute scan.

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