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Abstract #4668

Semi-quantitative Parametric Evaluation of Parotid Gland Function Using Proton Density Magnetic Resonance Imaging

Yu-Chia Cheng1, Yi-Jui Liu2, Yi-Hsiung Lee3,4, Hing-Chiu Chang5, Hui-Chu Chiu6, Ta-Wei Chiu7, Kang Hsu8, Hsian-He Hsu4,9, and Chun-Jung Juan4,9

1Master 's Program of Biomedical Informatics and Biomedical Engineering of Feng Chia University, Taichung, Taiwan, Taichung, Taiwan, 2Department of Automatic Control Engineering, Feng Chia University, Taichung, Taiwan, Republic of China, 3Ph.D. program in Electrical and Communication Engineering in Feng Chia University, Taichung, Taiwan, Republic of China, 4Department of Radiology, Tri-Service General Hospital, Taipei, Taiwan, Republic of China, 5Department of Diagnostic Radiology, The University of Hong Kong, Hong Kong, 6Ph.D. program of Technology Management, Chung Hua University, Hsinchu, Taiwan, Republic of China, 7Department of Medicine, Taipei Medical University, Taipei, Taiwan, Republic of China, 8Department of Dentistry, National Defense Medical Center, Taipei, Taiwan, Republic of China, 9Department of Radiology, National Defense Medical Center, Taipei, Taiwan, Republic of China

The parotid gland function is evaluated by gustatory stimulation using scintigraphy in clinic. It is supposed to measure the water component of parotid gland using PD MRI instead of scintigraphy. In this study, we initially developed the evaluation of parotid gland function by PD MRI, and 10 healthy volunteers underwent double echo EPI with gustatory stimulation. Maximal drop ratio (MDR), time to peak (TTP), drop slope (DS), recovery slope (RS) and recovery ratio (RR) were calculated. The signal intensity dropped significantly after gustatory stimulation on PD image (P<0.01). MRI allows quantification of parotid gland function using semi-quantitative functional parameters.

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