Colorectal cancer (CRC) is one of the most common malignant tumors in gastrointestinal tract. Tumor recurrence and metastasis are still a major cause of death in rectal cancer patients. Epithelial-mesenchymal transition (EMT) is reported a critical process providing tumor cells with the ability to migrate and metastasize to distant sites, leading to a poor prognosis in CRC. The diffusion kurtosis imaging (DKI) could quantify non-Gaussian behavior of water diffusion and provide more precise information of tissue characteristics. Our study demonstrated that DKI could be used to identify EMT in CRC xenograft models.
This abstract and the presentation materials are available to members only; a login is required.