Abstract #4405

Unified Proton and Fluorine Imaging of Small and Low Spin Density Samples at a Human Whole-Body 7 T MRI

Christian Bruns¹, Tim Herrmann¹, Markus Plaumann¹, Chang-Hyun Oh², Chulhyun Lee ³, Suchit Kumar⁴, and Johannes Bernarding¹

¹Department for Biometrics und Medical Informatics, Otto-von-Guericke University, Magdeburg, Germany, ²Department of Electronics and Information Engineering, and Korea Artificial Organ Center, Korea University, Seoul, Korea, Republic of, ³Bioimaging Research Team, Korea Basic Science Institute, Ochang, Korea, Republic of, ⁴Department of Biomicrosystem Technology and Korea Artificial Organ Center, Korea University, Seoul, Korea, Republic of

In order to provide a system, which allows imaging of ¹⁹F MR contrast agents, an in-house-built ¹⁹F/¹H transmit/receive system for 7 T was successfully tested in a human whole-body 7 T MRI system. This system enables the measurement of concentrations of 1.85 mM. For this approach we used a ¹⁹F tuned coil which provided still enough signal gain at the proton frequency to allow ¹H imaging for comparison. This showed the possibility of using ¹⁹F as contrast agents with a quite simple coil design in comparison to other dual tuned approaches.

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