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Abstract #4398

Optimization of b-values in iShim diffusion-weighted MR imaging of the thyroid gland: to improve the visualization of malignant thyroid nodules and the accuracy in differentiating malignant from benign thyroid nodules

Qingjun Wang1, Qinglei Shi2, Tianyi Qian3, Alto Stemmer4, and Yong Guo1

1Department of Radiology, Chinese Navy General Hospital, Beijing, People's Republic of China, 2Scientific Marketing, Siemens Healthcare, People's Republic of China, 3MR Collaobration, HC NEA MR COL, Siemens Healthcare, People's Republic of China, 4MR Application Predevelopment, Siemens Healthcare GmbH

To investigate the optimal b-values of diffusion-weighted imaging (DWI), a prototype sequence with integrated slice-specific shimming (iShim) was applied for visualizing thyroid malignant nodules and making accurate differentiation between benign and malignant nodules. DWI images were acquired with five b-values including 0, 800, 1000, 2000 and 3000 sec/mm2. The results show that the iShim-DWI with b-value of 800 s/mm2 can present the clearest delineation of malignant thyroid nodules and that the images with b-value of 3000 s/mm2 had the best performances in differentiating malignant from benign thyroid nodules.

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Abstract