Microsatellite instability (MSI) is the condition of genetic hypermutability that results from impaired DNA mismatch repair (MMR). High levels of microsatellite instability (MSI-H) is regarded as a prognostic marker and predictor of the response to chemotherapy in colorectal cancer (CRC). This study presented a multi-parametric radionics classifier for preoperative and individualized prediction of MSC-H status in CRC patients. The potential application of this radiomics approach may aid the prognostic evaluation and decision-making in CRC patients.
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