Abstract #4250

A morphological classification of primary central nervous system lymphoma: new insights of the imaging analysis to facilitate treatment planning

Jing Liu^1,2, Kannie W.Y. Chan³, Bin Zhang¹, Guan Shu Liu², and Shui Xing Zhang¹

¹Department of Radiology, Guangdong Academy of Medical Sciences/Guangdong General Hospital, Guangzhou, People's Republic of China, ²Russell H. Morgan Department of Radiology and Radiological Sciences, The Johns Hopkins University School of Medicine, Baltimore, MD, United States, ³Department of Mechanical and Biomedical Engineering, City University of Hong Kong, Hong Kong, People's Republic of China

A preliminary classification of primary central nervous system lymphoma (PCNSL) was reported based on the MRI radiographical features. We classified the 90 PCNSL patients based on the T1 contrast-enhanced MRI findings and assessed treatment responses. The goal is to provide some guidelines and additional information for diagnosis and treatment planning. We categorized these patients into four distinctive types of PCNSL according to the T1 findings and observed the treatment response rate, which we found the highest in type Ia. This could potentially facilitate the diagnosis and treatment plan of PCNSL in a routine clinical setting.

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