Abstract #4186

Active and passive fMRI for preoperative localization of motor function areas in brain tumor patients

Chen Niu¹, Xiao Ling¹, Pan Lin², Kun Zhang³, Xin Liu⁴, Liping Guo¹, Wenfei Li¹, Hao Song², Ming Zhang¹, and Maode Wang⁵

¹Department of Medical Imaging, The First Affiliated Hospital of Xi'An Jiaotong University, Xi'An, People's Republic of China, ²Key Laboratory of Biomedical Information Engineering of Education Ministry, Institute of Biomedical Engineering, Xi’an Jiaotong University, ³Department of Electronics Engineering, Northwestern Polytechnical University, ⁴Technical University Munich, ⁵Department of neurosurgery, The First Affiliated Hospital of Xi'An Jiaotong University, Xi'An, People's Republic of China

The aim of this study is to investigate whether there is consistency between active and passive movement in patients with brain tumors. Two motor tasks (active and passive hand movement) were applied to brain tumor patients. Our results demonstrate that there is no statistical difference of activation intensity between active hand movement and passive hand movement in patients with brain tumors. Our results suggest that passive movement fMRI provides a potential method for presurgical mapping in cases where patients are unable to comply with task instructions.

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