Abstract #3896

Fast Magnetic Resonance Fingerprinting of Mouse Brain Using a Spiral Trajectory

Yuning Gu¹, Charlie Wang¹, Christian Anderson¹, Yuchi Liu¹, Dan Ma¹, Yun Jiang¹, Mark A. Griswold^1,2, Chris A. Flask^1,2,3, and Xin Yu^1,2,4

¹Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH, United States, ²Department of Radiology, Case Western Reserve University, Cleveland, OH, United States, ³Department of Pediatrics, Case Western Reserve University, Cleveland, OH, United States, ⁴Department of Physiology and Biophysics, Case Western Reserve University, Cleveland, OH, United States

In this study we developed spiral-based MRF sequences for fast T₁ and T₂ mapping of mouse brain at 7T. A variable density spiral trajectory that fully sampled the inner 10×10 k-space with 4 interleaves enabled up to 6-fold acceleration for both MRF-bSSFP and MRF-FISP sequences, corresponding to a 3-min scan to acquire 1024 time frames for simultaneous T₁ and T₂ mapping.

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