Abstract #3888

Intensity inhomogeneity correction of whole body fat-water images using fat and water fraction information on a 3T PET/MR scanner

Therese Sjöholm¹, Simon Ekström¹, Filip Malmberg^1,2, Robin Strand^1,2, Magnus Johansson¹, Lars Lind³, Mathias Engström⁴, Håkan Ahlström^1,5, and Joel Kullberg^1,5

¹Radiology, Uppsala University, Uppsala, Sweden, ²Centre for Image Analysis, Uppsala University, Uppsala, Sweden, ³Medical Sciences, Uppsala University, Uppsala, Sweden, ⁴Applied Science Laboratory, GE Healthcare, Uppsala, Sweden, ⁵Antaros Medical, Mölndal, Sweden

We describe and evaluate a method for intensity non-uniformity correction of whole-body fat-water MR data acquired with both surface and body coils on a 3T PET/MRI system. The proposed method consists of two steps. Abrupt station intensity changes are first supressed, followed by correction of smooth intensity changes using fat and water fraction information. Visual and quantitative evaluations of 42 corrected fat-water datasets show that the method gives improved adipose and lean tissue uniformity for both surface and body coil acquisitions. This renders the data suitable for continued analysis in a whole-body imaging framework.

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