Non-Cartesian multi-shot sequences (e.g. spiral) offer several benefits over Cartesian counterparts in the context of high spatial resolution diffusion weighted imaging (DWI), including reduced B0 & T2* artifacts, as well as improved SNR resulting from lower TE. However, their main drawback of the above scheme is the sensitivity of the multi-shot imaging to motion artifacts. To achieve motion compensation, the multi-shot reconstruction methods rely on a phase-calibration procedure, during which an estimate of motion induced phase map is computed. Not only is the phase-calibration step time consuming, it also involves heavy optimization of parameters. The main focus of this work is to develop a phase calibration-free motion-compensated reconstruction for multi-shot non-Cartesian diffusion imaging.
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