Abstract #3856

Comparison of Compressed Sensing Accelerated TOF MRA of the Neck with Conventional TOF MRA and Ultrasound in Clinical Cases

Takayuki YAMAMOTO¹, Tomohisa OKADA², Yasutaka FUSHIMI¹, Koji FUJIMOTO³, Akira YAMAMOTO¹, Peter SPEIER⁴, Michaela SCHMIDT⁴, Yutaka NATSUAKI⁵, and Kaori TOGASHI¹

¹Diagnostic Imaging and Nuclear Medicine, Kyoto University, Graduate School of Medicine, Kyoto, Japan, ²Human Brain Research Center, Kyoto University, Graduate School of Medicine, Kyoto, Japan, ³Center for Advanced Imaging Innovation and Research (CAI2R) and Bernard and Irene Schwartz Center of Biomedical Imaging, New York University School of Medicine, Ner York, NY, United States, ⁴Siemens Healthcare GmbH, ⁵Siemens Medical Solutions USA, Inc.

Compressed sensing (CS) can accelerate time-of-flight magnetic resonance angiography (TOF MRA) of the neck. The whole length of carotid arteries from the aortic arch to the skull base was scanned in 2 minutes with an acceleration factor of 7.5. Iterative reconstruction that exploits regularization in 3 spatial directions required less than 3 minutes on a GPU. The degree of stenosis at carotid bifurcation for 22 patients was subjectively evaluated on maximum intensity projection images. Results of CS accelerated TOF MRA and conventional TOF MRA were compared with stenotic rates measured by ultrasound, and showed an excellent correlation.

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